Combined drug therapy of hemorrhoidal bleeding

Hemorrhoidal disease is one of the most common proctological pathologies. The main risk factors are physical inactivity, obesity, pregnancy, and chronic constipation, including dysynergic bowel movements. Systemic bioflavonoids (diosmin and hesperidin) demonstrate high efficacy, especially in the early stages of the disease. These substances strengthen blood vessels, reduce inflammation and improve microcirculation. Studies confirm that the combination of systemic flavonoids with topical agents such as sodium alginate accelerates the regression of symptoms. Sodium alginate in the form of candles has hemostatic, wound-healing and anti-inflammatory effects. When comparing the isolated use of bioflavonoids (Venarus® ) and combination therapy (Venarus® and Venaproct Alium), it was demonstrated that the combination of drugs is more effective in reducing the frequency of bleeding, reducing the size of hemorrhoids and reducing the frequency of relapses. The presented authors’ own experience demonstrates that the use of Venarus® and Venaproсt Allium drugs is effective in bleeding hemorrhoids. The results of treatment of 23 patients (11 men/12 women), aged 43 ± 5 years, who came for an initial consultation with complaints of blood discharge from the anus during defecation and who had not previously undergone colon examination, were analyzed. The use of a combination of Venarus® and Venaproct Alium, taking into account the therapeutic effects of each of the drugs, may be promising not only as an independent conservative therapy for hemorrhoids, but also at the stage of rehabilitation after surgical interventions, this requires further research.