Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H2O2-induced injury in PC12 cells

Our study explores a new biological transformation approach through solid-state fermentation (SSF) with Shiraia bambusicola Henn. on SMB. This study demonstrated that the SSF may reduce the cytotoxicity and enhance the antioxidant capacity of SMB in PC12 cells, thus paving the way for safer and more efficacious applications in the future. FSSMB may be an effective substitute for traditional Chinese medicine SMB for resistance to oxidative stress.