Anaesthetic Management of Child with Fanconi Anaemia for Emergency Lower Limb Surgery: A Case Report and Review of Literature

Fanconi anaemia is a rare, autosomal recessive bone marrow failure syndrome characterised by congenital anomalies and haematological abnormalities. Literature on anaesthetic management is limited due to its heterogeneous presentation and scarcity of clinical trials addressing anaesthetic considerations; with most information derived from case reports, we report successful anaesthetic management of a 7-year-old child with a history of allogeneic bone marrow transplant for correction of pancytopenia, presenting for an emergency lower limb surgery, emphasises the importance of meticulous perioperative care, an individualised plan focused on preventing and managing perioperative complications, is essential as these patients need as a thorough evaluation of congenital, syndromic and tumour-related complications as well as careful attention to haematological deficiencies.

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Journal
Journal of onco-anaesthesiology and perioperative medicine.
Published
2025-05-01
DOI
https://doi.org/10.4103/joapm.joapm_39_24
Primary Topic
Folate and B Vitamins Research
Type
article
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article

Anaesthetic Management of Child with Fanconi Anaemia for Emergency Lower Limb Surgery: A Case Report and Review of Literature

Anju Annie Paul, Sunil Kumar Valasareddy, B. Hariharansudhan
Journal of onco-anaesthesiology and perioperative medicine.
Folate and B Vitamins Research
article

Anaesthetic Management of Child with Fanconi Anaemia for Emergency Lower Limb Surgery: A Case Report and Review of Literature

Anju Annie Paul, Sunil Kumar Valasareddy, B. Hariharansudhan
article en

Abstract

Fanconi anaemia is a rare, autosomal recessive bone marrow failure syndrome characterised by congenital anomalies and haematological abnormalities. Literature on anaesthetic management is limited due to its heterogeneous presentation and scarcity of clinical trials addressing anaesthetic considerations; with most information derived from case reports, we report successful anaesthetic management of a 7-year-old child with a history of allogeneic bone marrow transplant for correction of pancytopenia, presenting for an emergency lower limb surgery, emphasises the importance of meticulous perioperative care, an individualised plan focused on preventing and managing perioperative complications, is essential as these patients need as a thorough evaluation of congenital, syndromic and tumour-related complications as well as careful attention to haematological deficiencies.

Journal of onco-anaesthesiology and perioperative medicine.Vol. 2(2)
Broomfield Hospital (GB), Tata Trusts (IN)
Openalex Percentile: Top 80%
Folate and B Vitamins Research
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Anaesthetic Management of Child with Fanconi Anaemia for Emergency Lower Limb Surgery: A Case Report and Review of Literature — Anju Annie Paul, Sunil Kumar Valasareddy, et al. · Journal of onco-anaesthesiology and perioperative medicine. (2025) | TGRS Research Map | TGRS