Assessing Motor Cortex Excitability and Its Relationship with Cortical Atrophy in Alzheimer’s Dementia
Patients with AD have decreased cortical thickness in the motor cortex and higher motor cortex excitability. This suggests that cortical excitability may be a marker of neurodegeneration in AD.
Authors
- Bruce G. Pollock (ORCID: https://orcid.org/0000-0003-0802-3998)
- Daniel M. Blumberger (ORCID: https://orcid.org/0000-0002-8422-5818)
- Zafiris Jeff Daskalakis (ORCID: https://orcid.org/0000-0001-9502-0538)
- Benoit H. Mulsant (ORCID: https://orcid.org/0000-0002-0303-6450)
- Corinne E. Fischer (ORCID: https://orcid.org/0000-0002-1047-0167)
- Reza Zomorrodi (ORCID: https://orcid.org/0000-0002-1648-843X)
- Michael Joseph (ORCID: https://orcid.org/0000-0002-0068-230X)
- Tarek K. Rajji (ORCID: https://orcid.org/0000-0002-8324-2560)
- Sanjeev Kumar (ORCID: https://orcid.org/0000-0002-8115-353X)
- Gifty Asare
- Aristotle N. Voineskos (ORCID: https://orcid.org/0000-0003-0156-0395)
- Hiba Alhabbal
- Renee P Lawson (ORCID: https://orcid.org/0009-0008-2216-7326)
Institutions
- St. Michael's Hospital (CA)
- Centre for Addiction and Mental Health (CA)
- University of Toronto (CA)
- York University (CA)
- UC San Diego Health System (US)
- University of California San Diego (US)
- Toronto Dementia Research Alliance (CA)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1017/cjn.2025.79
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amgen
- Alzheimer's Drug Discovery Foundation
- Biogen
- Patient-Centered Outcomes Research Institute
- BrightFocus Foundation
- University of Washington
- University of Massachusetts
- Fondation Brain Canada
- National Alliance for Research on Schizophrenia and Depression
- Wellcome Trust
- Centre for Addiction and Mental Health Foundation
- BrainsWay
- Consortium canadien en neurodégénérescence associée au vieillissement
- University of Toronto
- Novo Nordisk
- National Institutes of Health
- Canadian Institutes of Health Research
- National Institute on Aging
- National Institute of Mental Health