Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling
Modulating intestinal homeostasis is a promising approach for treating liver fibrosis in patients with WD. Therefore, GDL may serve as a useful agent for treating WD-associated liver fibrosis.
Authors
- Yuya Wen
- Jie Chen (ORCID: https://orcid.org/0000-0003-1558-7564)
- Jingyu Zeng (ORCID: https://orcid.org/0000-0002-5892-6098)
- Chenling Zhao (ORCID: https://orcid.org/0000-0002-6894-787X)
- Danqing Liu (ORCID: https://orcid.org/0000-0001-6191-4429)
- Wei Dong (ORCID: https://orcid.org/0000-0002-8644-6251)
- Wenming Yang (ORCID: https://orcid.org/0000-0003-1047-5328)
- Lulu Tang (ORCID: https://orcid.org/0000-0003-2362-1363)
- Ting Dong (ORCID: https://orcid.org/0009-0000-7050-9820)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Wuhan City Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.3389/fphar.2025.1586171
- Citations
- 2
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- National Natural Science Foundation of China