Association of fetal growth trajectory with mitochondrial DNA copy number in the cord blood of newborns: evidence from a birth cohort

Our findings indicate that different intrauterine growth patterns are present in fetuses with normal birth weights. In male infants, the "consistently low" intrauterine trajectory pattern was associated with decreased neonatal mtDNAcn. The effective detection of and intervention in fetal intrauterine growth patterns may help prevent metabolic health events early in life.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-06-09
DOI
https://doi.org/10.3389/fped.2025.1569702
Primary Topic
Birth, Development, and Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of fetal growth trajectory with mitochondrial DNA copy number in the cord blood of newborns: evidence from a birth cohort

Junwei Li, Aifen Zhou, Lulu Song, Zhongqiang Cao et al.
Frontiers in Pediatrics
Birth, Development, and Health
article

Association of fetal growth trajectory with mitochondrial DNA copy number in the cord blood of newborns: evidence from a birth cohort

Junwei Li, Aifen Zhou, Lulu Song, Zhongqiang Cao, Chao Xiong, Youjie Wang, Luli Xu, Kai Chen, Xiaoxuan Fan
article en

Abstract

Our findings indicate that different intrauterine growth patterns are present in fetuses with normal birth weights. In male infants, the "consistently low" intrauterine trajectory pattern was associated with decreased neonatal mtDNAcn. The effective detection of and intervention in fetal intrauterine growth patterns may help prevent metabolic health events early in life.

Frontiers in PediatricsVol. 13
Wuhan Children's Hospital (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 82%
Birth, Development, and Health
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