Study protocol: The efficacy of mushroom to prevent cognitive decline in at-risk middle-aged adults and young-olds living in the community
Cognitive function including Mini Mental State Examination, Rey Auditory Verbal Learning Test, Symbol Digit Modality test, Clinical Dementia Rating etc. along with mental health and biological markers will be measured at baseline, 1 year, and 2 years after baseline.
Authors
- Kaisy Xinhong Ye (ORCID: https://orcid.org/0000-0002-6924-9213)
- Tih-Shih Lee (ORCID: https://orcid.org/0000-0002-0788-422X)
- Su Lin Lim (ORCID: https://orcid.org/0000-0001-8478-3193)
- Kai Xuan Lim (ORCID: https://orcid.org/0000-0002-9519-6127)
- Yinxia Chao (ORCID: https://orcid.org/0000-0003-1185-3511)
- Lei Feng (ORCID: https://orcid.org/0000-0002-4414-9910)
- Jiatong Shan (ORCID: https://orcid.org/0000-0001-8641-7760)
- Luwen Cao (ORCID: https://orcid.org/0009-0006-1794-1271)
- Wei Ma (ORCID: https://orcid.org/0000-0002-2952-7944)
- Mihir Gandhi (ORCID: https://orcid.org/0000-0002-8902-2710)
- Irwin K. Cheah (ORCID: https://orcid.org/0000-0001-9817-468X)
- Jian Chen (ORCID: https://orcid.org/0000-0003-3782-3468)
- Na Li (ORCID: https://orcid.org/0000-0003-3810-0907)
- Yizhen Xie (ORCID: https://orcid.org/0000-0001-6805-6180)
- Jianian Guo
Institutions
- National University of Singapore (SG)
- Singapore General Hospital (SG)
- Guangdong Academy of Sciences (CN)
- Guangzhou First People's Hospital (CN)
- Duke-NUS Medical School (SG)
- Changchun University of Chinese Medicine (CN)
- National Neuroscience Institute (SG)
- Institute of Microbiology (CN)
- National University Hospital (SG)
- National University Health System (SG)
- Signature Research (United States) (US)
- Singapore Clinical Research Institute (SG)
- South China University of Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-06-09
- DOI
- https://doi.org/10.3389/fnagi.2025.1588493
- Citations
- 2
- Primary Topic
- Medicinal Plants and Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Medical Research Council
- National Medical Research Council