Integrated analysis of microbiome and host transcriptome revealed correlations between tissue microbiota and tumor progression in early-stage papillary thyroid carcinoma
In addition to characterizing the tissue microbiome and host gene expression in PTC patients, we further explored the roles of microbe-gene/cell interactions in PTC. The results provide candidate biomarkers for exploring the molecular mechanisms of tissue microbiome in tumorigenesis and tumor progression of PTC.
Authors
- Xinyun Xu (ORCID: https://orcid.org/0000-0002-2980-9378)
- Jiahao Pan (ORCID: https://orcid.org/0009-0003-6360-0337)
- Chen Shen (ORCID: https://orcid.org/0000-0003-3535-8494)
- Sheng Liu (ORCID: https://orcid.org/0000-0002-4058-4413)
- Xinyu Wang (ORCID: https://orcid.org/0000-0003-0806-4335)
- Xiaojun Chen (ORCID: https://orcid.org/0000-0002-0021-7483)
- Xiuwen Tong
Institutions
- Tongji University (CN)
- Shanghai Changzheng Hospital (CN)
- Hainan General Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.3389/fcimb.2025.1571341
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Shanghai Municipal Health Commission
- Tongji University