New insights into the pathological mechanism of varicocoele and its association with abnormal vascular remodeling in varicocoele patients
The pathological changes in morphology and overexpression of OPN in SMCs indicates a possible spermatic vascular transition from the contractile to secretory phenotype. This abnormal vascular remodeling might be associated with the reflux in the spermatic veins of VC patients.
Authors
- Y G L Zhang
- Shuangyong Sun
- Hanshu Wang (ORCID: https://orcid.org/0000-0002-9996-5114)
- Hongqiang Wang (ORCID: https://orcid.org/0000-0003-1885-7611)
- Tao Jing (ORCID: https://orcid.org/0000-0002-5103-7829)
- Qian Lin
- Lei Yu (ORCID: https://orcid.org/0000-0002-0386-4192)
- Ling Fu (ORCID: https://orcid.org/0009-0003-3764-5523)
- W. Li
- Yu Pan (ORCID: https://orcid.org/0009-0000-3832-1668)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Yantaishan Hospital (CN)
- Qingdao Women and Children's Hospital (CN)
Publication Details
- Journal
- Andrology
- Published
- 2025-06-08
- DOI
- https://doi.org/10.1111/andr.70080
- Primary Topic
- Bone and Dental Protein Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00