Recombinant Chitinase 3-like 1 Alleviates Liver Transplantation-induced Cold Ischemia/Reperfusion Injury by Promoting M2 Polarization of Kupffer Cells
rCHI3L1 alleviated rat hepatic cold IRI by inducing KCs M2 polarization via activating the Janus kinase 1/signal transducer and activator of transcription 3 axis, potentially providing a research basis for treating clinical hepatic IRI.
Authors
- Zhongjun Wu (ORCID: https://orcid.org/0000-0002-1627-0633)
- Dadi Peng
- Dengliang Lei
- Tengxiang Chen (ORCID: https://orcid.org/0000-0001-6907-1374)
- Kezhen Zong (ORCID: https://orcid.org/0000-0003-2233-5488)
- Liqing Jiang (ORCID: https://orcid.org/0000-0001-6360-0052)
- Chao Yu
- Yihua Wang (ORCID: https://orcid.org/0000-0001-5561-0648)
- Hang Yang (ORCID: https://orcid.org/0000-0002-4627-7027)
- Song Xiang
- Zuotian Huang
Institutions
- Guiyang Medical University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Transplantation
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1097/tp.0000000000005433
- Citations
- 1
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.01