The Impact of Polygenic Risk, Parental Separation, and Parental Relationship Discord on Heavy Episodic Drinking Across Adolescence and Young Adulthood in a High-Risk Sample
Genetic risk and exposure to parental separation and discord are associated with the course of HED, with some differences across continental groups.
Authors
- Jessica E. Salvatore (ORCID: https://orcid.org/0000-0001-5504-5087)
- Carolyn E. Sartor (ORCID: https://orcid.org/0000-0002-1622-1970)
- Fazil Alıev (ORCID: https://orcid.org/0000-0001-8357-4699)
- Danielle M. Dick (ORCID: https://orcid.org/0000-0002-1636-893X)
- Grace Chan (ORCID: https://orcid.org/0000-0002-1257-6889)
- Jacquelyn L. Meyers (ORCID: https://orcid.org/0000-0003-3863-8555)
- Kathleen Keenan Bucholz (ORCID: https://orcid.org/0000-0003-3794-0736)
- Howard J. Edenberg (ORCID: https://orcid.org/0000-0003-0344-9690)
- Vivia V. McCutcheon (ORCID: https://orcid.org/0000-0002-2694-5438)
- Samuel Kuperman (ORCID: https://orcid.org/0000-0002-5995-1981)
- Sally I‐Chun Kuo (ORCID: https://orcid.org/0000-0002-6192-1001)
- Marc A. Schuckit (ORCID: https://orcid.org/0000-0002-2323-7858)
- Dongbing Lai (ORCID: https://orcid.org/0000-0001-7803-580X)
- John R. Kramer (ORCID: https://orcid.org/0000-0002-1321-7087)
- Sarah J. Brislin (ORCID: https://orcid.org/0000-0003-4303-8124)
- Chella Kamarajan
- Martin H. Plawecki (ORCID: https://orcid.org/0000-0003-0708-9514)
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Iowa (US)
- University of Connecticut (US)
- SUNY Downstate Health Sciences University (US)
- Washington University in St. Louis (US)
- Johnson University (US)
- University of California San Diego (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- JAACAP Open
- Published
- 2025-06-08
- DOI
- https://doi.org/10.1016/j.jaacop.2025.06.001
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism
- National Institute on Drug Abuse