Characterization of Ventilatory Drive in Community-Dwelling Adults with Chronic Spinal Cord Injury

Independently breathing adults with chronic SCI have P0.1 values within normal range. This suggests their intrinsic resting ventilatory drive recovers from potentially elevated states in the acute phase of injury and is sufficient to sustain ventilation. The significant correlation between P0.1 and body mass has not been reported in the general population and suggests that body mass, P0.1, and ventilatory drive are tightly coupled in adults with SCI despite independent breathing ability. The potential for increased body mass-induced strain on the respiratory pump after SCI may have implications for breathing during daily activities and exercise which should be explored in future research.

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Publication Details

Journal
Archives of Rehabilitation Research and Clinical Translation
Published
2025-06-08
DOI
https://doi.org/10.1016/j.arrct.2025.100481
Primary Topic
Spinal Cord Injury Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Characterization of Ventilatory Drive in Community-Dwelling Adults with Chronic Spinal Cord Injury

Emily J. Fox, Michela Mir, Gordon S. Mitchell, Tommy W. Sutor et al.
Archives of Rehabilitation Research and Clinical Translation
Spinal Cord Injury Research
article

Characterization of Ventilatory Drive in Community-Dwelling Adults with Chronic Spinal Cord Injury

Emily J. Fox, Michela Mir, Gordon S. Mitchell, Tommy W. Sutor, Alicia K. Vose
article en

Abstract

Independently breathing adults with chronic SCI have P0.1 values within normal range. This suggests their intrinsic resting ventilatory drive recovers from potentially elevated states in the acute phase of injury and is sufficient to sustain ventilation. The significant correlation between P0.1 and body mass has not been reported in the general population and suggests that body mass, P0.1, and ventilatory drive are tightly coupled in adults with SCI despite independent breathing ability. The potential for increased body mass-induced strain on the respiratory pump after SCI may have implications for breathing during daily activities and exercise which should be explored in future research.

Archives of Rehabilitation Research and Clinical TranslationVol. 7(3)
University of Florida (US), Brooks Rehabilitation Clinical Research Center (US), Brenau University (US), Florida College (US)
Congressionally Directed Medical Research Programs
Openalex Percentile: Top 81%
Spinal Cord Injury Research
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