Determination of the spectrum of osteomyelitis pathogens in the Southern Federal District of Russia as a fundamental factor in creating local protocols for providing care (empirical antibiotic therapy)

Introduction: Osteomyelitis is a serious complication of diseases of the musculoskeletal system. Materials and methods: 332 patients aged 18 to 65 years with osteomyelitis of the extremity bones were examined. A set of studies was carried out, including microbiological studies with determination of antibiotic sensitivity. Results: According to the localization of the pathological process, damage to the tibia prevailed – 113 (34 %) patients. The etiology of osteomyelitis is dominated by staphylococci. Chronication of the process occurs due to gram-negative bacteria with a high level of resistance. Conclusions: Monitoring of pathogens is an important link in creating local protocols for empirical antibacterial therapy for osteomyelitis of the extremities.

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Publication Details

Journal
Journal of Volgograd State Medical University
Published
2025-06-08
DOI
https://doi.org/10.19163/1994-9480-2025-22-1-150-156
Primary Topic
Orthopedic Infections and Treatments
Type
article
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article

Determination of the spectrum of osteomyelitis pathogens in the Southern Federal District of Russia as a fundamental factor in creating local protocols for providing care (empirical antibiotic therapy)

В. В. Алексеев, Olga Yu. Kutsevalova, N.S. Alekseeva, Г В Лобанов et al.
Journal of Volgograd State Medical University
Orthopedic Infections and Treatments
article

Determination of the spectrum of osteomyelitis pathogens in the Southern Federal District of Russia as a fundamental factor in creating local protocols for providing care (empirical antibiotic therapy)

В. В. Алексеев, Olga Yu. Kutsevalova, N.S. Alekseeva, Г В Лобанов, Sergey T. Ivanyan, Oleg B. Jerelei, Leonid S. Gubar
article en

Abstract

Introduction: Osteomyelitis is a serious complication of diseases of the musculoskeletal system. Materials and methods: 332 patients aged 18 to 65 years with osteomyelitis of the extremity bones were examined. A set of studies was carried out, including microbiological studies with determination of antibiotic sensitivity. Results: According to the localization of the pathological process, damage to the tibia prevailed – 113 (34 %) patients. The etiology of osteomyelitis is dominated by staphylococci. Chronication of the process occurs due to gram-negative bacteria with a high level of resistance. Conclusions: Monitoring of pathogens is an important link in creating local protocols for empirical antibacterial therapy for osteomyelitis of the extremities.

Journal of Volgograd State Medical UniversityVol. 22(1)
Rostov State Medical University (RU), Republican Scientific and Practical Center of Neurology and Neurosurgery (BY), Donetsk National Medical University (UA)
Openalex Percentile: Top 77%
Orthopedic Infections and Treatments
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