Clinical case of acquired inhibitory form of hemophilia a in an elderly patient
The formation of circulating autoantibodies capable of inhibiting factors of the blood coagulation system is accompanied by the occurrence of spontaneous and/or post-traumatic bleeding in patients without a history of previous disorders of the hemostatic system. One of the reasons for the development of such conditions is acquired hemophilia. Aim: Identification of the mechanisms of development of the acquired inhibitory form of hemophilia A in elderly patients using the example of our own clinical observation. Material and methods: Analysis of a clinical case and analysis of current scientific literature. Results: The presented clinical case allowed us to study the pathogenesis, principles of diagnosis and treatment of acquired coagulopathy. Conclusions: Knowledge about the development mechanisms and features of the course of the acquired inhibitory form of hemophilia A should help the clinician in the early diagnosis of this coagulopathy and, as a consequence, the timely initiation of treatment aimed at preserving the patient’s life.
Authors
- Liliya M. Salimova (ORCID: https://orcid.org/0000-0003-4186-6049)
- Alsu F. Molostvova (ORCID: https://orcid.org/0000-0001-6996-9985)
Institutions
- Kazan State Medical University (RU)
- City Clinical Hospital (RU)
Publication Details
- Journal
- Journal of Volgograd State Medical University
- Published
- 2025-06-08
- DOI
- https://doi.org/10.19163/1994-9480-2025-22-1-164-166
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00