The effect of dark deprivation on the dynamics of body weight and the level of Klotho protein in the blood of animals

The effect of 30-day dark deprivation (light-dark mode 24/0 h) on the dynamics of body weight and the level of Klotho protein in the blood of 4-month-old white mongrel female rats was studied. It was found that prolonged dark deprivation is accompanied by an increase in animal body weight against the background of a statistically significant decrease in the level of melatonin and Klotho protein in blood serum. It is a marker of premature aging. Melatonin had a protective effect on the body of animals, contributed to a decrease in body weight against the background of an increase in the content of Clotho protein in blood serum.