Wellens Syndrome Corollaries: A Call for Definition with a Case Series

Introduction: First described in 1982, the Wellens wave is an electrocardiographic (ECG) finding indicative of a critical lesion of the left anterior descending artery. These T-wave findings are classically found in ECG leads V2 and V3, although they may extend into the lateral leads V4-V6. Case Series: We present three cases of patients with Wellens waves that were found only in leads V3 and V4 and did not include V2. Conclusion: We suggest that the classical definition of T-waves in leads V2 and V3 is not the only manifestation of Wellens waves to indicate pathology. Wellens waves found in two contiguous leads in leads V1-V6 can be considered Wellens corollaries, thereby requiring the same emergent treatment as classical Wellens syndrome. We also recognize the need for a consensus on the inclusion criteria of Wellens syndrome, particularly the laboratory and ECG findings that define the disease.

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Publication Details

Journal
Clinical Practice and Cases in Emergency Medicine
Published
2025-06-08
DOI
https://doi.org/10.5811/cpcem.35877
Primary Topic
Combustion and Detonation Processes
Type
article
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article

Wellens Syndrome Corollaries: A Call for Definition with a Case Series

Addison Rayne Sparks, Patrick Bruss
Clinical Practice and Cases in Emergency Medicine
Combustion and Detonation Processes
article

Wellens Syndrome Corollaries: A Call for Definition with a Case Series

Addison Rayne Sparks, Patrick Bruss
article en

Abstract

Introduction: First described in 1982, the Wellens wave is an electrocardiographic (ECG) finding indicative of a critical lesion of the left anterior descending artery. These T-wave findings are classically found in ECG leads V2 and V3, although they may extend into the lateral leads V4-V6. Case Series: We present three cases of patients with Wellens waves that were found only in leads V3 and V4 and did not include V2. Conclusion: We suggest that the classical definition of T-waves in leads V2 and V3 is not the only manifestation of Wellens waves to indicate pathology. Wellens waves found in two contiguous leads in leads V1-V6 can be considered Wellens corollaries, thereby requiring the same emergent treatment as classical Wellens syndrome. We also recognize the need for a consensus on the inclusion criteria of Wellens syndrome, particularly the laboratory and ECG findings that define the disease.

Clinical Practice and Cases in Emergency MedicineVol. 9(3)
University of Toledo Medical Center (US), University of Toledo (US)
Openalex Percentile: Top 83%
Combustion and Detonation Processes
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Wellens Syndrome Corollaries: A Call for Definition with a Case Series — Addison Rayne Sparks, Patrick Bruss · Clinical Practice and Cases in Emergency Medicine (2025) | TGRS Research Map | TGRS