Post-treatment time to symptom resolution and associated factors in a cohort of Ugandan men with urethral discharge syndrome
Delayed TTR was associated with prior UDS episodes. Negative tests for common curable STIs were associated with delayed TTR suggesting the possible role of other infectious or non-infectious etiologies. The underlying mechanisms of delayed SR, e.g., reinfection, treatment failure, or dysregulated mucosal immunity, warrant further exploration.
Authors
- Johan H. Melendez (ORCID: https://orcid.org/0000-0001-6586-051X)
- Peter Kyambadde (ORCID: https://orcid.org/0000-0002-9606-218X)
- Matthew M. Hamill (ORCID: https://orcid.org/0000-0002-1277-819X)
- Yukari Carol Manabe (ORCID: https://orcid.org/0000-0001-8619-5598)
- Rosalind M. Parkes-Ratanshi (ORCID: https://orcid.org/0000-0001-9297-1311)
- Courtney Pasco (ORCID: https://orcid.org/0000-0003-3918-2115)
- Annet A. Onzia (ORCID: https://orcid.org/0000-0002-6741-1512)
- Ethan Gough (ORCID: https://orcid.org/0000-0001-5265-7731)
- Yisi Liu (ORCID: https://orcid.org/0000-0001-5924-0816)
- Junyi Zhou (ORCID: https://orcid.org/0009-0006-2499-4742)
Institutions
- Johns Hopkins University (US)
- University of Cambridge (GB)
- Johns Hopkins Medicine (US)
- Ministry of Health (UG)
- Infectious Diseases Institute (UG)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-06-08
- DOI
- https://doi.org/10.1186/s12879-025-11196-8
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Johns Hopkins University
- National Institutes of Health