Association of uric acid with all-cause mortality in acute coronary syndrome patients with T2DM
A J-shaped curve characterizes the association between UA levels and all-cause mortality in patients with T2DM and ACS. Patients with an appropriate UA level exhibited better prognosis. Post-hoc analyses revealed stronger point estimates for the prognostic effect of UA in patients with suboptimal glycemic control, although interaction testing did not achieve statistical significance. Further studies with larger subgroup samples are warranted.
Authors
- Jianjun Yan (ORCID: https://orcid.org/0000-0002-1233-1136)
- Bing-Yang Zhou
- Le Wang (ORCID: https://orcid.org/0000-0002-0375-3177)
- Qi Zhang (ORCID: https://orcid.org/0000-0001-9916-8919)
- Hongliang Cong (ORCID: https://orcid.org/0000-0001-6970-6077)
- Cuiying Zhang (ORCID: https://orcid.org/0000-0003-4770-2598)
Institutions
- Tianjin Municipal Education Commission (CN)
- Tianjin Chest Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Atherosclerosis Plus
- Published
- 2025-06-08
- DOI
- https://doi.org/10.1016/j.athplu.2025.06.001
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Tianjin City