The Impact of Volume Removal by Hemodialysis on Elevated NT-proBNP Levels in Patients With Hypervolemia

Volume expansion is the main factor causing elevated NT-proBNP levels in acute or chronic HD patients. Reducing predialysis volume expansion with a single hemodialysis session has no impact on NT-proBNP level. Therefore, repeating the NT-proBNP level post-HD has no clinical value. Our data suggest that NT-proBNP is a useful cardiac biomarker for volume expansion, and its elevated level predicts high cardiovascular mortality and recurrent hospitalizations in acute and chronic HD patients.

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Journal
Cureus
Published
2025-06-08
DOI
https://doi.org/10.7759/cureus.85554
Citations
1
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
Field-Weighted Citation Impact
2.25
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article

The Impact of Volume Removal by Hemodialysis on Elevated NT-proBNP Levels in Patients With Hypervolemia

Mohammad Tinawi, Bahar Bastani
1 citations
Cureus
Cardiac Arrest and Resuscitation
2.25
article

The Impact of Volume Removal by Hemodialysis on Elevated NT-proBNP Levels in Patients With Hypervolemia

Mohammad Tinawi, Bahar Bastani
article en
1 citations

Abstract

Volume expansion is the main factor causing elevated NT-proBNP levels in acute or chronic HD patients. Reducing predialysis volume expansion with a single hemodialysis session has no impact on NT-proBNP level. Therefore, repeating the NT-proBNP level post-HD has no clinical value. Our data suggest that NT-proBNP is a useful cardiac biomarker for volume expansion, and its elevated level predicts high cardiovascular mortality and recurrent hospitalizations in acute and chronic HD patients.

CureusVol. 17(6)
Saint Louis University (ES), Saint Louis University (US)
Openalex Percentile: Top 14%
Cardiac Arrest and Resuscitation
2.25
DOIOpen Access PDFOpenAlex
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The Impact of Volume Removal by Hemodialysis on Elevated NT-proBNP Levels in Patients With Hypervolemia — Mohammad Tinawi, Bahar Bastani · Cureus (2025) | TGRS Research Map | TGRS