Refining housekeeping genes and demonstrating their potential for clinical and experimental applications
We have identified novel HKGs useful in breast cancer research and proved that they exhibit more stable expression compared to previously known HKGs. These findings may offer researchers and clinicians a more reliable normalization standard for gene expression analysis, potentially enhancing the accuracy of breast cancer diagnosis and the selection of personalized treatments.
Authors
- Hye Jung Lee (ORCID: https://orcid.org/0000-0002-6046-5120)
- Kyung Won Hwang
- Ye Ji Shin (ORCID: https://orcid.org/0000-0001-8169-5024)
- Jae Won Yun (ORCID: https://orcid.org/0000-0002-9029-8036)
- Hong Sook Kim (ORCID: https://orcid.org/0000-0003-0971-0853)
Institutions
- Veterans Health Service Medical Center (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Computers in Biology and Medicine
- Published
- 2025-06-08
- DOI
- https://doi.org/10.1016/j.compbiomed.2025.110546
- Citations
- 1
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81