THE EFFECTIVENESS OF BASAL-BOLUS INSULIN THERAPY IN COMPARISON WITH SLIDING-SCALE INSULIN THERAPY IN SURGICAL PATIENTS WITH DIABETES

Goal. To investigate the effectiveness of basal-bolus insulin therapy in comparison with sliding-scale therapy in diabetic patients who underwent surgery. Materials and methods. The study involved adult patients, aged 18 to 85 years, with diabetes, diagnosed more than 3 months ago, who had scheduled or emergency surgical procedures at the Republican Clinical Hospital of Makhachkala. Patients with blood glucose levels of 150-400 mg/dl were randomly assigned to two groups: basal bolus therapy (insulin glargine and glulisine) and sliding scale therapy. The main indicators of the assessment were the average daily glucose levels and the frequency of postoperative complications. Results. The basal-bolus therapy group showed lower glucose levels and a lower incidence of wound infections compared to the SSI group. The frequency of combined adverse outcomes was significantly higher in the SSI group, which confirms the advantage of the basal-bolus approach in the surgical context. Conclusions. Basal-bolus insulin therapy provides more stable glycemic control and reduces the incidence of infectious complications in patients who have undergone surgery. It is recommended that this treatment regimen be considered to improve outcomes in inpatient patients with diabetes.