Clinicopathological study of Xanthogranulomatous oophoritis-a 6-year retrospective study in a tertiary care hospital

Background: Xanthogranulomatous oophoritis is a rare chronic inflammatory process involving ovary .Essentially it affects ovaries alone and or fallopian tubes focally or entirely forming and adnexal mass in the pelvic cavity. In this study, we aimed to analyse the clinicopathological features of xanthogranulomatous oophoritis and its prognostic implication. Methods: This was a retrospective study conducted over a period of 6years.A total of 18 cases were evaluated. Result: Xanthogranulomatous oophoritis was seen most commonly in the age group of 41-50 years. Abdominal pain was the most common clinical presentation. Microscopically there was chronic inflammatory cells, foamy histiocytes and multinucleated giant cells in the ovarian stroma. Though histopathological examination is gold standard procedure, combined routine histopathology and immunohistochemistry was required for a conclusive diagnosis in difficult cases. Conclusion: To conclude, though the condition is rare, due to its tendency to extend to the surrounding tissues and formation of mass lesion, it closely mimics ovarian malignancy both clinically and radiologically leading to close follow up of these patients for optimal patient care.