Population pharmacokinetics of isavuconazole in hematologic patients: implications for model-informed precision dosing
BSA and serum ALB were identified as covariates influencing isavuconazole clearance in adult hematologic patients. Further studies are needed to better characterize the absorption of isavuconazole and implications on dosage recommendations, especially for higher proposed doses.
Authors
- José Germán Sánchez‐Hernandez (ORCID: https://orcid.org/0000-0002-2985-3686)
- Lourdes Vázquez-López
- Diego Peña-Lorenzo (ORCID: https://orcid.org/0000-0003-3737-9336)
- Noemí Rebollo (ORCID: https://orcid.org/0000-0002-7955-9979)
- Aránzazu Zarzuelo Castañeda (ORCID: https://orcid.org/0000-0002-9169-4372)
- María José Otero (ORCID: https://orcid.org/0000-0001-6468-8842)
- Irene Conde-González
Institutions
- Universidad de Salamanca (ES)
- Instituto de Investigación Biomédica de Salamanca (ES)
Publication Details
- Journal
- European Journal of Pharmaceutical Sciences
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1016/j.ejps.2025.107157
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00