TOXICITY (TOXIC MATERIAL) SCORE AND COCKTAIL TREATMENTS (COVI WONDER) FOR LONG COVID: A RETROSPECTIVE COHORT STUDY

Introduction: A long Covid represents systemic, disabling conditions of more than three months that associated with acute SARS-CoV-2 infections or post-acute sequelae of Covid (PASC). It can be diagnosed on clinical bases without a definite diagnostic tool nor a treatment. The study was done to evaluate both the toxicity score of the blood for the diagnosis of and the Cocktail medication for the healing of long Covid.Methods: Among patients who visited our clinic from June 2022 to January 2025, 48 patients with long Covid-19 finished all the series of peripheral blood smear, blood chemistry and blood toxicology tests more than twice. While 10 patients did not have cocktail medications to treat their long Covid, 38 patients were treated by the recommended protocols including Cocktail medications of our clinic. Among 38 patients, one outlier, who showed familial allergic reactions to PEG (polyethylene glycol) was removed from the Wilcoxon matched paired t tests.Results: The mean age of the untreated 10 patients was 59.7 ± 9.55 years old and that of treated 37 patients was 56.1 ± 13.61 years. Untreated patients with Cocktail medication showed minimal improvements of their previous symptoms in the following visits, and the toxicity score of the blood increased significantly from 12.90 ± 7.20 to 18.30 ± 5.25 (Wilcoxon test: z = - 2.536, p= 0.011). Treated 37 patients with cocktail medication showed significant symptomatic improvements in their follow-up visits and the toxicity score of the blood significantly decreased from 12.92 ± 5.18 to 7.76 ± 2.99 (Wilcoxon Test: z = - 4.783, p < 0.001).Conclusion: The results show that the toxicity (toxic material) score of the blood can be a diagnostic tool for and the Cocktail medications can be a healing protocol for the long Covid.