Synergistic effects of compound plant extracts and <i>Lactobacillus plantarum</i> on osteogenesis: prebiotic potential and mechanistic insights from metabolomics and molecular docking
The combined application of CPE and L. plantarum could promote bone formation through multiple targets and pathways. These findings highlight the potential of plant extract-probiotic synergy in developing functional foods for bone health, offering a promising dietary strategy to prevent osteoporosis. © 2025 Society of Chemical Industry.
Authors
- Shilong Jiang (ORCID: https://orcid.org/0000-0001-6975-0844)
- Jiayuan Luo (ORCID: https://orcid.org/0000-0003-3800-0973)
- Mingjie Jia (ORCID: https://orcid.org/0000-0002-1293-1406)
- Fangfei Li (ORCID: https://orcid.org/0000-0002-0342-3872)
- Yangyang Chai (ORCID: https://orcid.org/0000-0002-3646-7820)
- Xu Zhang (ORCID: https://orcid.org/0000-0003-4798-0520)
- Yihong Bao
- Qinggang Xie
Institutions
- Education Department of Heilongjiang Province (CN)
- Northeast Forestry University (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1002/jsfa.14412
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00