Utility of ThinPreps in Enhancing Diagnostic Precision of Fine Needle Aspiration (FNA) Samples from Lymph Nodes

Objectives: Fine needle aspiration (FNA) is a widely used, minimally invasive technique for evaluating lymph node lesions. Rapid on-site evaluation (ROSE) during FNA procedures enhances diagnostic adequacy but may extend procedure times. ThinPrep, an automated liquid-based cytology technique, offers a standardized method for specimen preparation that may improve diagnostic precision by providing uniform cell distribution and reducing background blood and debris. This study aims to compare ThinPrep and Cytospin preparations of lymph node FNA samples to assess their impact on cytomorphologic quality and diagnostic accuracy.

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Publication Details

Journal
Academic Pathology
Published
2025-04-01
DOI
https://doi.org/10.1016/j.acpath.2025.100177
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Utility of ThinPreps in Enhancing Diagnostic Precision of Fine Needle Aspiration (FNA) Samples from Lymph Nodes

A. Aravind, Varsha Manucha, Bilal Khan, Navneet Kaur et al.
Academic Pathology
Salivary Gland Tumors Diagnosis and Treatment
article

Utility of ThinPreps in Enhancing Diagnostic Precision of Fine Needle Aspiration (FNA) Samples from Lymph Nodes

A. Aravind, Varsha Manucha, Bilal Khan, Navneet Kaur, W. Cavett
article en

Abstract

Objectives: Fine needle aspiration (FNA) is a widely used, minimally invasive technique for evaluating lymph node lesions. Rapid on-site evaluation (ROSE) during FNA procedures enhances diagnostic adequacy but may extend procedure times. ThinPrep, an automated liquid-based cytology technique, offers a standardized method for specimen preparation that may improve diagnostic precision by providing uniform cell distribution and reducing background blood and debris. This study aims to compare ThinPrep and Cytospin preparations of lymph node FNA samples to assess their impact on cytomorphologic quality and diagnostic accuracy.

Academic PathologyVol. 12(2)
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Salivary Gland Tumors Diagnosis and Treatment
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