Rechallenging Unresectable Hepatocellular Carcinoma with the STRIDE Regimen: A Case Report of Significant AFP Response after Atezolizumab-Bevacizumab Intolerance

This case suggests that rechallenging with the STRIDE regimen may provide significant clinical benefit in HCC patients intolerant to initial ICI therapy. However, further clinical trials are needed to confirm the efficacy and optimal use of ICI rechallenge strategies in HCC.

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Publication Details

Journal
Case Reports in Oncology
Published
2025-06-07
DOI
https://doi.org/10.1159/000546711
Citations
1
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
1.32
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article

Rechallenging Unresectable Hepatocellular Carcinoma with the STRIDE Regimen: A Case Report of Significant AFP Response after Atezolizumab-Bevacizumab Intolerance

James Doolin, Sugat Adhikari
1 citations
Case Reports in Oncology
Hepatocellular Carcinoma Treatment and Prognosis
1.32
article

Rechallenging Unresectable Hepatocellular Carcinoma with the STRIDE Regimen: A Case Report of Significant AFP Response after Atezolizumab-Bevacizumab Intolerance

James Doolin, Sugat Adhikari
article en
1 citations

Abstract

This case suggests that rechallenging with the STRIDE regimen may provide significant clinical benefit in HCC patients intolerant to initial ICI therapy. However, further clinical trials are needed to confirm the efficacy and optimal use of ICI rechallenge strategies in HCC.

Case Reports in OncologyVol. 18(1)
Lahey Medical Center (US)
Openalex Percentile: Top 20%
Hepatocellular Carcinoma Treatment and Prognosis
1.32
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