Randomized Clinical Trials in Cerebrovascular Neurosurgery: Analysis of Discontinuation and Nonpublication Prevalence and Trends

Premature discontinuation was common among cerebrovascular trials in neurosurgery and frequently attributed to difficulties with patient enrollment. Nonpublication was especially common among discontinued trials. Our findings may highlight opportunities to improve research efficiency and potentially improve outcomes for patients with cerebrovascular diseases.

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Publication Details

Journal
World Neurosurgery
Published
2025-06-07
DOI
https://doi.org/10.1016/j.wneu.2025.124159
Primary Topic
Acute Ischemic Stroke Management
Type
article
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0.00
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article

Randomized Clinical Trials in Cerebrovascular Neurosurgery: Analysis of Discontinuation and Nonpublication Prevalence and Trends

Scott Y. Rahimi, Lydia Kaoutzani, Molly Butler
World Neurosurgery
Acute Ischemic Stroke Management
article

Randomized Clinical Trials in Cerebrovascular Neurosurgery: Analysis of Discontinuation and Nonpublication Prevalence and Trends

Scott Y. Rahimi, Lydia Kaoutzani, Molly Butler
article en

Abstract

Premature discontinuation was common among cerebrovascular trials in neurosurgery and frequently attributed to difficulties with patient enrollment. Nonpublication was especially common among discontinued trials. Our findings may highlight opportunities to improve research efficiency and potentially improve outcomes for patients with cerebrovascular diseases.

World NeurosurgeryVol. 199
Augusta University (US), Augusta University Health (US)
Openalex Percentile: Top 81%
Acute Ischemic Stroke Management
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