Model-informed drug development of Mim8 – a next-generation bispecific antibody for treatment of haemophilia A

Model-informed drug development was used to design a novel treatment paradigm for patients living with haemophilia A by utilising a tiered-dosing strategy with Mim8, to be evaluated in phase 3 trials.

Authors

Mads Kreilgaard (ORCID: https://orcid.org/0000-0002-1957-4341)
Paula Persson
Irina Matytsina

Institutions

Novo Nordisk (Denmark) (DK)

Publication Details

Journal: European Journal of Pharmaceutical Sciences
Published: 2025-06-07
DOI: https://doi.org/10.1016/j.ejps.2025.107162
Citations: 2
Primary Topic: Hemophilia Treatment and Research
Type: article
Field-Weighted Citation Impact: 3.54

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article

Model-informed drug development of Mim8 – a next-generation bispecific antibody for treatment of haemophilia A

Mads Kreilgaard, Paula Persson, Irina Matytsina

Jun 7, 2025

2 citations

European Journal of Pharmaceutical Sciences

Hemophilia Treatment and Research

3.54

article

Model-informed drug development of Mim8 – a next-generation bispecific antibody for treatment of haemophilia A

Mads Kreilgaard, Paula Persson, Irina Matytsina

June 7, 2025article en

2 citations

Abstract

European Journal of Pharmaceutical SciencesVol. 212

Novo Nordisk (Denmark) (DK)

Good health and well-being

Openalex Percentile: Top 8%

Hemophilia Treatment and Research

3.54

DOI Open Access PDF OpenAlex

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Model-informed drug development of Mim8 – a next-generation bispecific antibody for treatment of haemophilia A — Mads Kreilgaard, Paula Persson, et al. · European Journal of Pharmaceutical Sciences (2025) | TGRS Research Map | TGRS