Species turnover within cystic fibrosis lung microbiota is indicative of acute pulmonary exacerbation onset
Here, we illustrate that changes in turnover of the lung microbiota of pwCF can be indicative of PEx onset in considerable advance of when treatment would normally be initiated. This offers translational potential to enable early detection of PEx and consequent timely intervention. Video Abstract.
Authors
- Leah Cuthbertson (ORCID: https://orcid.org/0000-0002-9604-2269)
- Lauren Hatfield
- Chris Gast (ORCID: https://orcid.org/0000-0003-1101-4048)
- Damian Rivett (ORCID: https://orcid.org/0000-0002-1852-6137)
- Helen Gavillet (ORCID: https://orcid.org/0000-0002-0815-830X)
- Matthew J. Hardman (ORCID: https://orcid.org/0000-0002-6423-5074)
- Ryan Marsh (ORCID: https://orcid.org/0000-0002-3790-1721)
Institutions
- Manchester Metropolitan University (GB)
- University of Leicester (GB)
- Northumbria University (GB)
- Swansea University (GB)
Publication Details
- Journal
- Microbiome
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s40168-025-02143-5
- Citations
- 1
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Cystic Fibrosis Trust
- Natural Environment Research Council