Sarcospan, a candidate gene of fat distribution, may affect lipid storage in adipocytes
Although the epigenetic downregulation of Sspn showed only marginal effects on adipogenesis, associations of SSPN expression in human adipose tissue with parameters of fat distribution and glucose homeostasis make it a promising candidate for further studies addressing metabolic processes in adipose tissue.
Authors
- Adhideb Ghosh (ORCID: https://orcid.org/0000-0002-5160-4571)
- Anne Hoffmann (ORCID: https://orcid.org/0000-0003-3258-3397)
- Maria Keller (ORCID: https://orcid.org/0000-0003-4026-8530)
- Christian Wolfrum (ORCID: https://orcid.org/0000-0002-3862-6805)
- Falko Noé (ORCID: https://orcid.org/0009-0002-3360-5455)
- Matthias Blüher (ORCID: https://orcid.org/0000-0003-0208-2065)
- Luise Müller (ORCID: https://orcid.org/0000-0002-5417-2647)
- Péter Kovács (ORCID: https://orcid.org/0000-0002-0290-5423)
- Samantha Aurich
- Katharina Anastasia Dinter
Institutions
- ETH Zurich (CH)
- University Hospital Leipzig (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Molecular and Cellular Endocrinology
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1016/j.mce.2025.112602
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Deutsche Diabetes Gesellschaft