Heterogeneous characteristics of γδ T cells in peripheral blood of diffuse large B-cell lymphoma
We identified genetic subtypes of γδ T cells with distinct genotypic and clinical characteristics in DLBCL patients. Expression levels within these subgroups emerged as potential indicators for patient outcomes and as crucial factors in shaping therapeutic strategies. These insights significantly advance our understanding of intricate relationships among cellular subgroups and their roles in influencing disease progression and patient prognosis.
Authors
- Xiuli Wu (ORCID: https://orcid.org/0000-0002-5202-6515)
- Penglin Wang
- Xiaofang Wu (ORCID: https://orcid.org/0000-0002-3782-7701)
- Jiamian Zheng
- Tingzhuang Yi (ORCID: https://orcid.org/0000-0002-4709-7247)
- Wen-Pu Lai
- Jiayi Zhan
- Zhen‐Yi Jin
Institutions
- Jinan University (CN)
- Guangzhou Experimental Station (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Stomatology Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Biomarker Research
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s40364-025-00795-x
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Jinan University
- Guangdong Provincial People's Hospital
- Basic and Applied Basic Research Foundation of Guangdong Province