KRT5high TP63-expressing urothelial basal cells act as a driver to bladder urothelium regeneration in rabbit
In summary, bioengineering urothelium with KRT5<sup>high</sup> TP63-expressing basal cells on a capsule vascular bed offers a promising strategy for bladder tissue engineering and provides a model for drug screening and bladder disease research.
Authors
- Fang Chen (ORCID: https://orcid.org/0000-0002-0242-331X)
- Mingming Yu (ORCID: https://orcid.org/0000-0001-9957-6568)
- Yue Hong (ORCID: https://orcid.org/0000-0002-9866-0589)
- Yichen Huang (ORCID: https://orcid.org/0009-0002-7229-7782)
- Jiasheng Chen (ORCID: https://orcid.org/0000-0003-2945-8034)
- Hua Xie (ORCID: https://orcid.org/0000-0002-0207-4500)
- Lin Wang (ORCID: https://orcid.org/0000-0002-6271-3351)
- Yiqing Lv
Institutions
- Hainan University (CN)
- Shanghai Stomatological Hospital (CN)
- Shanghai Sixth People's Hospital (CN)
- Shanghai Children's Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s13287-025-04417-z
- Citations
- 1
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Science and Technology Innovation Plan Of Shanghai Science and Technology Commission