Update on disseminated cryptococcosis in non-HIV infected children
Disseminated cryptococcosis in children often presents with fever, respiratory and neurological symptoms, with the lungs, central nervous system, and lymph nodes being the most frequently involved organs. Most cases do not have immunodeficiency or underlying diseases, and blood tests often reveal eosinophilia and elevated IgE levels. The positive detection rates of pathogens are relatively high in blood cultures, cerebrospinal fluid, bone marrow cultures, and lymph node biopsies. The majority of patients achieved favorable therapeutic outcomes with combination therapy.
Authors
- Lin Huiying
- Xiao Wu (ORCID: https://orcid.org/0000-0002-9998-8084)
- Xiaobo Zhang (ORCID: https://orcid.org/0000-0002-7573-9200)
- Guangmin Nong (ORCID: https://orcid.org/0000-0002-3219-0895)
Institutions
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- The Italian Journal of Pediatrics/Italian journal of pediatrics
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s13052-025-02011-w
- Citations
- 1
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- Natural Science Foundation of Guangxi Province
- Education Department of Guangxi Zhuang Autonomous Region