Uncovering the bequeathing potential of apoptotic mesenchymal stem cells via small extracellular vesicles for its enhanced immunomodulatory and regenerative ability
This study concludes that apoptosis induction can be considered as minimum manipulation strategy to enhance the immunoregulatory and regenerative potential of MSCs-sEVs, thereby expanding their implication in immune disorder.
Authors
- Mohini Mendiratta
- Sujata Mohanty (ORCID: https://orcid.org/0000-0002-0047-4914)
- Yashvi Sharma (ORCID: https://orcid.org/0000-0002-5264-6028)
- Meenakshi Mendiratta
- Ranjit Kumar Sahoo (ORCID: https://orcid.org/0000-0002-4130-724X)
- Neena Malhotra
Institutions
- Stem Cell Institute (PA)
- DR. B.R.A. Institute Rotary Cancer Hospital (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s13287-025-04370-x
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- All-India Institute of Medical Sciences