Asymmetric Synthesis of Either Enantiomer of β-Butadienyl Amines by Isoprenylation of Davis–Ellman Imines

The asymmetric synthesis of either enantiomer of β-butadienyl amines from a single starting material is described. Reversal of the diastereoselectivity is achieved by simply tuning the reaction conditions. This methodology provides excellent yields (up to 98%) and high diastereomeric ratios (<i>dr</i> up to 98:2) and exhibits a broad substrate scope.