Mapping the immune cells of the testis: Key insights into sexual maturation
Multi-omics integration reveals dynamic immune remodeling during testicular maturation. These findings underscore the potential involvement of B cells in local immune surveillance while identifying maturation-associated signaling axes between stromal and immune cells. This comprehensive mapping of testicular leukocyte dynamics significantly advances our understanding of reproductive immunology and lays foundation for investigating immune-mediated testicular pathologies.
Authors
- Zunpan Fan (ORCID: https://orcid.org/0009-0007-4922-7395)
- Chenzhao Feng (ORCID: https://orcid.org/0000-0001-6018-7768)
- Xiaoyu Wu (ORCID: https://orcid.org/0000-0003-2985-0917)
- Huiping Zhang (ORCID: https://orcid.org/0000-0002-5728-6658)
- Yongfeng Wang (ORCID: https://orcid.org/0000-0002-9660-345X)
- Kai Zhao (ORCID: https://orcid.org/0000-0002-4456-8461)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Andrology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1111/andr.70077
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease