Dynamic changes in vasohibin and nitric oxide signaling following surgical resection of head and neck squamous cell carcinoma
This study demonstrated that dynamic changes in VASH and NO signaling following tumor resection could serve as a potential indicator of tumor angiogenesis. Our findings suggest that the overall activity of the VASH pathway in leukocytes was reduced after tumor removal, highlighting the potential of leukocyte physiology as a novel biomarker for cancer surveillance and control.
Authors
- Chih‐Cherng Lu (ORCID: https://orcid.org/0000-0001-6834-7156)
- Shung‐Tai Ho (ORCID: https://orcid.org/0000-0001-8334-8675)
- Shyh‐Kuan Tai (ORCID: https://orcid.org/0000-0001-5644-3589)
- Tso‐Chou Lin (ORCID: https://orcid.org/0000-0003-0131-2586)
- You‐Hsiang Chu (ORCID: https://orcid.org/0000-0001-9312-2776)
- Hsiang-Ling Wu
- Cheng‐Hsien Wu (ORCID: https://orcid.org/0000-0002-0613-7214)
- Ying‐Hsuan Tai
Institutions
- Tri-Service General Hospital (TW)
- National Yang Ming Chiao Tung University (TW)
- Kaohsiung Medical University (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Taipei Veterans General Hospital (TW)
- Taipei Medical University-Shuang Ho Hospital (TW)
- Taipei Medical University (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s12957-025-03853-8
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Taipei Veterans General Hospital