Comparison among Early-Onset, Late-Onset, and Conventional-Onset Adenocarcinoma of Stomach and Esophagogastric Junction: a Retrospective Study
A decreasing trend in the EOGC surgical population has been observed over the past 20 years at West China Hospital. Compared to COGC patients, EOGC patients had a higher proportion of females, SRCC cases, poorer differentiation, and lower Her-2 expression, but demonstrated a better survival outcome. Conversely, the worst prognosis outcome was observed in EOGC patients within the AEG subgroup. LOGC was an independent negative factor for survival results. Chemotherapy did not improve the prognosis for EOGC and LOGC patients at stage II and III.
Authors
- Xiaolong Chen (ORCID: https://orcid.org/0000-0003-3474-7711)
- Jian-Kun Hu (ORCID: https://orcid.org/0000-0001-6905-3934)
- Yuqing Liang (ORCID: https://orcid.org/0000-0001-8421-752X)
- Lin-Yong Zhao (ORCID: https://orcid.org/0000-0003-0884-4657)
- Valentin Kudriashov (ORCID: https://orcid.org/0000-0003-2444-9104)
- Xiao-Hai Song (ORCID: https://orcid.org/0000-0001-6986-5772)
- Kun Yang
- Kai Liu (ORCID: https://orcid.org/0000-0001-6159-1156)
- Weihan Zhang (ORCID: https://orcid.org/0000-0002-9498-8245)
- Li‐Fei Sun (ORCID: https://orcid.org/0009-0003-1797-4055)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Sichuan Cancer Hospital (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s12957-025-03867-2
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Sichuan University
- West China Hospital, Sichuan University