Quantitation of PET spatial extent as a potential adjunct to visual interpretation of [18F]flortaucipir imaging: TAU-SPEX
TAU-SPEX was strongly associated with visual read, NFT Braak-V/VI pathology and cognition, and might be useful in clinical settings as a potential adjunct to [<sup>18</sup>F]flortaucipir visual interpretation.
Authors
- Sebastian Palmqvist (ORCID: https://orcid.org/0000-0002-9267-1930)
- Rik Ossenkoppele (ORCID: https://orcid.org/0000-0003-1584-7477)
- Erik Stomrud (ORCID: https://orcid.org/0000-0002-0841-5580)
- Wiesje M. van der Flier (ORCID: https://orcid.org/0000-0001-8766-6224)
- Sergey Shcherbinin
- Emma M. Coomans (ORCID: https://orcid.org/0000-0002-4289-9101)
- Elsmarieke van de Giessen
- Vikas Kotari (ORCID: https://orcid.org/0000-0002-4211-9400)
- Ruben Smith (ORCID: https://orcid.org/0000-0001-7147-0112)
- Niklas Mattsson (ORCID: https://orcid.org/0000-0002-8885-7724)
- Oskar Hansson (ORCID: https://orcid.org/0000-0001-8467-7286)
- Bastiaan van Tol
- Ian Kennedy (ORCID: https://orcid.org/0000-0003-2684-1935)
- Michael J. Pontecorvo (ORCID: https://orcid.org/0000-0002-8419-7589)
- Colin Groot (ORCID: https://orcid.org/0000-0002-4384-0160)
- Yolande A.L. Pijnenburg (ORCID: https://orcid.org/0000-0003-2464-1905)
Institutions
- Eli Lilly (United States) (US)
- Malmö University (SE)
- Lund University (SE)
- Amsterdam Neuroscience (NL)
- Skåne University Hospital (SE)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1007/s00259-025-07384-y
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amsterdam University Medical Centers
- Alzheimer Nederland
- HORIZON EUROPE European Research Council