Identification and validation of blood leukocyte DNA methylation biomarkers for early detection of colorectal neoplasm
Blood leukocyte DNA methylation markers show significant potential for identifying high-risk populations for CRC. The identified markers could contribute to the development of novel, effective tools for CRC screening, facilitating precision screening strategies.
Authors
- Xiaoping Miao (ORCID: https://orcid.org/0000-0002-6818-9722)
- Yuelun Zhang (ORCID: https://orcid.org/0000-0001-7990-9003)
- Dong Wu (ORCID: https://orcid.org/0000-0002-7328-8207)
- Jianbo Tian (ORCID: https://orcid.org/0000-0001-9493-694X)
- Chenyu Luo (ORCID: https://orcid.org/0000-0001-8147-9540)
- Kai Song (ORCID: https://orcid.org/0000-0003-4459-7059)
- Fulan Hu (ORCID: https://orcid.org/0000-0002-2386-1503)
- Yuqing Chen (ORCID: https://orcid.org/0000-0003-3832-3836)
- Zhiliang He (ORCID: https://orcid.org/0009-0002-8318-891X)
- Xinran Cheng (ORCID: https://orcid.org/0009-0005-5320-1484)
- Na Li (ORCID: https://orcid.org/0000-0002-8463-7441)
- Bin Lu (ORCID: https://orcid.org/0000-0001-7184-2211)
- Hongda Chen (ORCID: https://orcid.org/0000-0001-6171-1162)
- Jiahui Luo (ORCID: https://orcid.org/0009-0006-7800-2577)
- Min Dai (ORCID: https://orcid.org/0009-0005-3951-3625)
- Yike Yan
Institutions
- Shenzhen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Wuhan University (CN)
- Tibet Autonomous Region People's Hospital (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1097/cm9.0000000000003681
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00