Culicoides allergens expressed in insect cells induce sulphidoleukotriene release from peripheral blood leukocytes of horses affected with insect bite hypersensitivity
Insect-cell-expressed <i>Culicoides</i> recombinant allergens are functionally relevant and will open new opportunities for the study of <i>Culicoides</i> hypersensitivity not only in horses but also potentially in human patients or other species. They will also greatly improve IBH diagnostics using cellular assays and IgE serology.
Authors
- Sara Björk Stefánsdóttir (ORCID: https://orcid.org/0000-0001-9560-7574)
- Jelena Mirkovitch
- Sigurbjörg Torsteinsdóttir (ORCID: https://orcid.org/0000-0002-3195-4937)
- Anja Ziegler (ORCID: https://orcid.org/0000-0002-8178-9159)
- Eliane Marti (ORCID: https://orcid.org/0000-0003-1284-4350)
- Sigrı́dur Jónsdóttir (ORCID: https://orcid.org/0000-0003-2576-9599)
Institutions
- University of Bern (CH)
- University of Iceland (IS)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.3389/fimmu.2025.1597233
- Citations
- 2
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 3.24
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Rannís
- College of Veterinary Medicine, Cornell University