IL-1beta expressing neutrophil extracellular traps in Legionella pneumophila infection
This study provides evidence that neutrophils react to L. pneumophila through phagocytosis, the production of ROS, and NET release. IL-1b on NETs could play a role in complicated LD cases. These findings contribute to the understanding of neutrophil-mediated immune responses in LD.
Authors
- Evangelia Xingi (ORCID: https://orcid.org/0000-0002-0852-2423)
- Myrto Koutantou
- Konstantinos Kambas (ORCID: https://orcid.org/0000-0002-9264-8458)
- Georgios Tsiotis (ORCID: https://orcid.org/0000-0002-3205-1342)
- Dimosthenis Chochlakis (ORCID: https://orcid.org/0000-0001-7370-7830)
- Theocharis Konstantinidis (ORCID: https://orcid.org/0000-0003-4296-3414)
- Anna Psaroulaki (ORCID: https://orcid.org/0000-0003-2078-9822)
- Emmanouil Angelakis (ORCID: https://orcid.org/0000-0002-2743-5165)
Institutions
- University of Crete (GR)
- Democritus University of Thrace (GR)
- Pasteur Hellenic Institute (GR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.3389/fimmu.2025.1573151
- Citations
- 2
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- European Commission