Gallbladder adenocarcinoma diagnosed retrospectively after initial resection of abdominal wall adenocarcinoma with unidentified primary source: a case report and review of the literature

Gallbladder carcinoma is the most common malignancy found within the biliary tract and is most often diagnosed incidentally after cholecystectomy is performed. Port-site metastasis discovered after removal of gallbladder carcinoma is not entirely unusual; however, recommendations for the definitive management of these metastasis sites do not yet exist. We report a rare case of incisional site seeding diagnosed prior to the discovery of gallbladder adenocarcinoma in a healthy 59-year-old woman with a history of open cholecystectomy performed in a different country. Ultimately, this patient's case was staged as stage IVb disease as determined by an extensive multidisciplinary tumor board discussion and was managed with observation, frequent physical exams, and surveillance imaging. Our patient's survival is 2 years 7 months to date after index cholecystectomy. The management of our unprecedented case of gallbladder carcinoma diagnosed retrospectively after the initial discovery of incisional site metastasis is a difficult one, and the management of unique oncologic scenarios should utilize a multidisciplinary tumor board approach.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-06-06
DOI
https://doi.org/10.3389/fonc.2025.1609239
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Gallbladder adenocarcinoma diagnosed retrospectively after initial resection of abdominal wall adenocarcinoma with unidentified primary source: a case report and review of the literature

So Un Kim, Sharmila Raju, Judi Ramiscal, Angel Guan et al.
Frontiers in Oncology
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Gallbladder adenocarcinoma diagnosed retrospectively after initial resection of abdominal wall adenocarcinoma with unidentified primary source: a case report and review of the literature

So Un Kim, Sharmila Raju, Judi Ramiscal, Angel Guan, Kendall Vignaroli, Kevin Perez, Carolyn S. Leach
article en

Abstract

Gallbladder carcinoma is the most common malignancy found within the biliary tract and is most often diagnosed incidentally after cholecystectomy is performed. Port-site metastasis discovered after removal of gallbladder carcinoma is not entirely unusual; however, recommendations for the definitive management of these metastasis sites do not yet exist. We report a rare case of incisional site seeding diagnosed prior to the discovery of gallbladder adenocarcinoma in a healthy 59-year-old woman with a history of open cholecystectomy performed in a different country. Ultimately, this patient's case was staged as stage IVb disease as determined by an extensive multidisciplinary tumor board discussion and was managed with observation, frequent physical exams, and surveillance imaging. Our patient's survival is 2 years 7 months to date after index cholecystectomy. The management of our unprecedented case of gallbladder carcinoma diagnosed retrospectively after the initial discovery of incisional site metastasis is a difficult one, and the management of unique oncologic scenarios should utilize a multidisciplinary tumor board approach.

Frontiers in OncologyVol. 15
Arrowhead Regional Medical Center (US)
Arrowhead Regional Medical Center
Openalex Percentile: Top 77%
Cholangiocarcinoma and Gallbladder Cancer Studies
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Gallbladder adenocarcinoma diagnosed retrospectively after initial resection of abdominal wall adenocarcinoma with unidentified primary source: a case report and review of the literature — So Un Kim, Sharmila Raju, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS