Performance of eight serum cytokine/chemokine biomarkers in discriminating between active and latent tuberculosis infection in Ghana
These findings confirm reports from other studies in different settings that LTBI and ATB express differential cytokine profiles that can be exploited as diagnostic biomarkers. Of note, the quantitative estimation of IL-12p70 may serve as a valuable marker for monitoring disease progression and treatment success in tuberculosis.
Authors
- Kwadwo Koram (ORCID: https://orcid.org/0000-0003-4274-6516)
- Kennedy Kwasi Addo (ORCID: https://orcid.org/0000-0002-5641-0274)
- Isaac Anim‐Baidoo (ORCID: https://orcid.org/0009-0000-8723-3365)
- Jones A. Amponsah
- John Tetteh (ORCID: https://orcid.org/0000-0002-1986-4103)
- Gloria Ivy Mensah (ORCID: https://orcid.org/0000-0002-6499-5946)
- Nana Boakye Alahaman
Institutions
- University of Ghana (GH)
- Noguchi Memorial Institute for Medical Research (GH)
- University for Development Studies (GH)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.3389/fimmu.2025.1600712
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Bill and Melinda Gates Foundation
- Wellcome Trust
- European Commission
- Noguchi Memorial Institute for Medical Research, University of Ghana
- European and Developing Countries Clinical Trials Partnership