Interrogation of macrophage-related prognostic signatures reveals a potential immune-mediated therapy strategy by histone deacetylase inhibition in glioma
These findings elucidate the molecular mechanisms of GAMs in glioma, uncover the immunological landscape of the tumor microenvironment, and identify potential therapeutic targets and drug action mechanisms.
Authors
- Jianshen Liang (ORCID: https://orcid.org/0009-0006-1539-8113)
- Xisen Wang (ORCID: https://orcid.org/0000-0002-6091-9217)
- Jikang Fan
- Xuya Wang (ORCID: https://orcid.org/0000-0002-8342-8672)
- Yaohua Li (ORCID: https://orcid.org/0000-0003-4225-6736)
- Chen Zhang (ORCID: https://orcid.org/0000-0002-9448-2965)
- Yiming Li (ORCID: https://orcid.org/0000-0002-1828-8765)
- Yiming Zhang (ORCID: https://orcid.org/0000-0002-2224-006X)
- Yu Zhang (ORCID: https://orcid.org/0000-0003-0978-2363)
- Tao Li (ORCID: https://orcid.org/0000-0002-5108-1774)
- Xuejun Yang (ORCID: https://orcid.org/0000-0001-7056-1223)
- Lei Chen (ORCID: https://orcid.org/0000-0002-6071-8888)
- Hao Ding (ORCID: https://orcid.org/0000-0003-3845-8925)
- Shengping Yu
Institutions
- Tianjin First Center Hospital (CN)
- Tianjin Medical University General Hospital (CN)
- Tianjin Huanhu Hospital (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Tianjin Medical University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.3389/fonc.2025.1554845
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Beijing Municipality