Serum and nasal lavage fluid eosinophil-derived neurotoxin levels and their determinants in adults
Adults with current asthma were more likely to have higher serum, but not NLF, EDN levels than those without asthma. Although serum EDN could be a promising marker in asthma, background determinants-such as sex, obesity, and atopy-should be considered when interpreting EDN levels.
Authors
- Jan Lötvall (ORCID: https://orcid.org/0000-0001-9195-9249)
- Reshed Abohalaka (ORCID: https://orcid.org/0000-0003-2803-2912)
- Daniil Lisik (ORCID: https://orcid.org/0000-0002-0220-5961)
- Göran Wennergren (ORCID: https://orcid.org/0000-0002-7010-7191)
- Madeleine Rådinger (ORCID: https://orcid.org/0000-0002-0652-7378)
- Saliha Selin Özuygur Ermiş (ORCID: https://orcid.org/0000-0003-3507-773X)
- Sebastian Schmeisser (ORCID: https://orcid.org/0000-0003-1910-7281)
- Magnus P. Borres (ORCID: https://orcid.org/0000-0002-9045-2304)
- Rani Basna (ORCID: https://orcid.org/0000-0001-7510-8460)
- Robert Movérare (ORCID: https://orcid.org/0000-0001-6611-5036)
- Linda Ekerljung (ORCID: https://orcid.org/0000-0001-5784-0041)
- Hannu Kankaanranta (ORCID: https://orcid.org/0000-0001-5258-0906)
- Roxana Mincheva (ORCID: https://orcid.org/0000-0002-6072-2748)
- Selin Ercan (ORCID: https://orcid.org/0009-0003-5887-0332)
- Bright I. Nwaru (ORCID: https://orcid.org/0000-0002-2876-6089)
- Carina Malmhäll (ORCID: https://orcid.org/0000-0001-6696-7570)
Institutions
- Uppsala University (SE)
- Tampere University (FI)
- Seinäjoki University of Applied Sciences (FI)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- Thermo Fisher Scientific (Sweden) (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1016/j.jacig.2025.100510
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Thermo Fisher Scientific
- Hjärt-Lungfonden
- Vetenskapsrådet
- Astma- och Allergiförbundet