Mannose-labelled magnetic nanoparticles for sentinel lymph node biopsy in oral squamous cell carcinoma: Initial results from a phase 1 clinical trial
This study demonstrates the procedural feasibility of a novel magnetic approach to SLNB in OSCC using a first-in-human magnetic tracer. These promising early results lay the foundation for an attractive next generation technique, and holds significant potential to increase adoption of SLNB in the complex head and neck lymphatic environment.
Authors
- Anil Shetty
- Aidan Cousins (ORCID: https://orcid.org/0000-0002-2986-422X)
- Andrew Foreman (ORCID: https://orcid.org/0000-0002-6560-6391)
- Giri Krishnan (ORCID: https://orcid.org/0000-0002-4196-9155)
- Andrew Dwyer
- Shridhar Krishnan
- James Badlani (ORCID: https://orcid.org/0000-0003-1166-8885)
- Deepak Dhatrak
- Suren Krishnan (ORCID: https://orcid.org/0000-0001-5675-1194)
- Eben Lloyd Rosenthal (ORCID: https://orcid.org/0000-0003-0294-5203)
- Benjamin Thierry (ORCID: https://orcid.org/0000-0002-6757-2842)
- Angela Walls (ORCID: https://orcid.org/0000-0001-9489-2991)
- Nynke van den Berg
- John‐Charles Hodge
Institutions
- University of South Australia (AU)
- Stanford Medicine (US)
- South Australian Health and Medical Research Institute (AU)
- The University of Adelaide (AU)
- Stanford University (US)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1016/j.ejso.2025.110221
- Citations
- 2
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.70
Funders
- Garnett Passe and Rodney Williams Memorial Foundation
- National Health and Medical Research Council