Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial
Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the Society for Healthcare Epidemiology of America central line-associated bloodstream infection prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for central venous access device insertion/postinsertion care, sutureless securement, connector type and decontamination method.
Authors
- Karina Charles (ORCID: https://orcid.org/0000-0002-8279-5155)
- Andrew J. Stewardson (ORCID: https://orcid.org/0000-0001-6805-1224)
- Kevan R. Polkinghorne (ORCID: https://orcid.org/0000-0002-9851-002X)
- Jessica Schults (ORCID: https://orcid.org/0000-0002-5406-9519)
- Sally Havers (ORCID: https://orcid.org/0000-0001-6362-6412)
- Aleece MacPhail (ORCID: https://orcid.org/0000-0002-2332-8186)
- Benjamin Lazarus (ORCID: https://orcid.org/0000-0001-7936-025X)
- Claire M. Rickard (ORCID: https://orcid.org/0000-0002-6341-7415)
- Niccolò Buetti (ORCID: https://orcid.org/0000-0002-8096-1834)
Institutions
- Queensland Health (AU)
- Inserm (FR)
- The University of Queensland (AU)
- Monash Medical Centre (AU)
- Princess Alexandra Hospital (AU)
- The Alfred Hospital (AU)
- University Hospital of Geneva (CH)
- Monash Health (AU)
- Alfred Health (AU)
- Monash University (AU)
- Geneva College (US)
Publication Details
- Journal
- American Journal of Infection Control
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1016/j.ajic.2025.06.003
- Citations
- 1
- Primary Topic
- Central Venous Catheters and Hemodialysis
- Type
- article
- Field-Weighted Citation Impact
- 2.52
Funders
- Tour de Cure
- Medical Research Council
- National Health and Medical Research Council