Tobacco smoking as a factor in the development of COPD and pulmonary tuberculosis

Objective. To study the relationship between tobacco smoking and the development of COPD and pulmonary tuberculosis. Material and methods. The analysis of domestic and foreign databases for the period from 2003 to 2024, including PubMed, MedLine, eLibrary.ru. The following keywords were used in the literature search: «tuberculosis», «smoking», «tobacco», «COPD», «functional lung disorders». Results. The most important factor in the development and progression of COPD is long-term exposure to harmful particles, gases, as well as tobacco smoking and infectious diseases, including tuberculosis. Meanwhile, tobacco consumption is a significant factor in the development of not only COPD, but also an active tuberculosis process. It is worth saying that smoking patients with pulmonary tuberculosis have low results of treatment, which leads to the progression of the tuberculosis process and relapses in the future. Also, a large number of studies indicate a wide prevalence of functional lung disorders in the development of pulmonary tuberculosis and active tobacco consumption. In this connection, it can be concluded that the development and course of pulmonary tuberculosis and COPD are closely interrelated, including in the presence of tobacco smoking, and may be associated not only with the development of functional lung disorders, but also with the onset of cardiovascular pathology. Conclusion. Significant problems in global health are the increase in the incidence of COPD and pulmonary tuberculosis. Smoking is one of the main factors in the development and more severe course of both COPD and pulmonary tuberculosis. An urgent area is the development and implementation of anti-smoking measures to eliminate tobacco dependence among patients with COPD and pulmonary tuberculosis.